Štěpán Vyskočil






The Scripps Institute, 10550 North Torrey Pines Road, La Jolla CA 92037, USA










medicinal chemistry, organic synthesis, asymmetric and total synthesis, organic stereochemistry, reaction mechanisms




Short CV:


1992 Ph.D. with Jiří Klinot and Martin Smrčina, Charles University, Prague, Czech Republic
1999 Assistant Professor at Department of Organic Chemistry, Charles University, Prague, Czech Republic
2000 - 2001 NATO fellow with Pavel Kočovský at University of Glasgow, UK
since 2003 postdoc with K.C. Nicolaou at The Scripps Institute, USA






2002 Alfred Bader Prize for Organic Chemistry from the Czech Chemical Society






Smrčina, M., Vyskočil, S., Hanuš, V., Polášek, M., Langer, V., Chew, B. G. M., Zax, D.B. Verrier, H., Harper, K., Claxton, T.A., Kočovský, P. The SN2 Reaction in Solid State. An Unusual, BAl2 Aminolysis of an Ester Group in Crystalline (+)-2-Amino-2'-hydroxy-3'-(methoxycarbonyl)-1,1'-binaphthyl Elucidated by X-ray Diffraction and Isotopic Labeling. New Experimental Evidence for Linearity in SN2 Substitutions. J. Am. Chem. Soc. 118: 487 (1996).
Belokon, Y. N., Kochetkov, K. A., Churkina, T. D., Ikonnikov, N. S., Chesnokov, A. A., Larionov, O. V., Singh, I., Parmar, V. S., Vyskočil, Š., Kagan, H. B. Asymmetric PTC C-Alkylation Catalyzed by Chiral Derivatives of Tartaric Acid and Aminophenols. Synthesis of (R)- and (S)-a-Amino Acids. J. Org. Chem. 65: 7041 (2000).
Vyskočil, S., Smrčina, M., Lorenc, M., Tislerová, I., Brooks, R., Kulagowski, J. J., Langer, V., Farrugia, L., Kočovský, P. Copper(II)-Mediated Oxidative Coupling of 2-Aminonaphthalene Homologues. Competition between the Straight Dimerization and the Formation of Carbazoles. J. Org. Chem. 66: 1359 (2001).
Belokon, Y.N., Kochetkov, K.A., Churkina, T.D., Ikonnikov, N.S., Larionov, O.V., Harutjunan, S.R., Vyskočil, Š., North, M., Kagan, H.B. Highly Efficient Synthesis of a-Amino Acids Under Phase Transfer Conditions Based on a Novel Catalyst/Substrate Pair. Angew. Chem. 40: 1948 (2001).
Kočovský, P., Vyskočil, Š., Smrčina, M. Non-Symmetrically Substituted 1,1'-Binaphthyls in Enantioselective Catalysis. Chem. Rev. 103: 3213 (2003).