Name:

Petr Váchal

Affiliation:

Merck, RY121S-271, Rahway, NJ 07065, USA

E-mail:

petr_vachal@merck.com

Research:

therapeutical areas of cardiovascular and immunosuppressants

Short CV:

1993-1998 MSc. with J. Svoboda, Department of Organic Chemistry, Institute of chemical Technology, Prague, Czech Republic
 
1998-2003 Ph.D. with E.N. Jacobsen, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, USA
 
since 2003 Senior Research Chemist, Merck Research Laboratories, Department of Basic Chemistry, Rahway, USA
 

Awards:

1998 Honor Award of Josef Hlavka in Organic Chemistry
 
1998-2001 Alfred Bader Fellowship in Chemistry
 
1999-2000 Bristol-Myers Squibb Fellowship
 
2001-2002 Eli Lilly Fellowship
 

Publications:

Sigman, M. S., Váchal, P., Jacobsen, E.N. A General Catalyst for the Asymmetric Strecker Reaction. Angew. Chem. Int. Ed. 39: 1279 (2000).
 
Váchal, P., Jacobsen, E.N. Enantioselective Catalytic Addition of HCN to Ketoimines. Catalytic Synthesis of Quaternary Amino Acids. Org. Lett. 2: 867 (2000).
 
Su, J.T., Váchal, P., Jacobsen, E.N. Practical Synthesis of a Soluble Schiff Base Catalyst for the Asymmetric Strecker Reaction. Adv. Synth. Catal. 343: 197 (2001).
 
Váchal, P., Jacobsen, E.N. Structure-Based Analysis and Optimization of a Highly Enantioselective Catalyst for the Strecker Reaction. J. Am. Chem. Soc. 124: 10012 (2002).
 
Váchal, P., Jacobsen, E.N. Cyanation of Carbonyl and Imino Groups. in Comprehensive Asymmetric Catalysis , E.N. Jacobsen, A. Pfaltz, Y. Yamamoto (Eds.), Springer-Verlag, Berlin, 117 (2004).