Name:

Dominik Rejman

Affiliation:

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 16610 Prague 6, Czech Republic

E-mail:

rejman@uochb.cas.cz

Web:

http://www.uochb.cas.cz

Research:

analogues of nucleosides, nucleotides, and oligonucleotides – synthesis and biological properties

Short CV:

2001-2002 Department of Chemistry, University of Sheffield, Great Britain
 
2004 Center for Drug Design, University of Minnesota, USA
 
since 2005 Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic
 

Awards:

2007 Alfred Bader Prize for Bioorganic Chemistry from the Czech Chemical Society
 

Publications:

Rejman, D., Masojídková, M., Rosenberg, I.: Nucleosidyl-O-methylphosphonates: A Pool of Mionomers for Modified Oligonucleotides. Nucleosides, Nucleotides & Nucleic Acids 71: 1683-1705 (2004).
 
Rejman, D., Olesiak, M., Chen, L.Q., Patterson, S.E., Wilson, D., Jayaram, H.N., Hedstrom, L., Pankiewicz, K.W.: Novel Methylenephosphophosphonate Analogues of Mycophenolic Adenine Dinucleotide. Inhibition of Inosine Monophosphate Dehydrogenase J. Med. Chem. 49: 5018-5022 (2006).
 
Rejman, D., Kočalka P., Buděšínský M., Pohl R., Rosenberg I.: Synthesis of Diastereomeric 3-hydroxy-4-pyrrolidinyl Derivatives of Nucleobases. Tetrahedron 63: 1243-1253 (2007).
 
Suk, D.H., Rejman, D., Dykstra, C., Pohl, R., Pankiewicz, K. W., Patterson, S.E.: Phosphonoxins: Rational Design and Discovery of a Potent Nucleotide anti-Giardia Agent. Bioorg. Med. Chem. Letters 17: 2811-2816 (2007).
 
Rejman, D., Kočalka, P., Buděšínský, M., Barvík, I., Rosenberg, I.: Stereospecific N-oxide-mediated Monoprotection of trans-3,4-dihydroxypyrrolidine Derivatives, Tetrahedron Asymm. 18: 2165-2174 (2007).